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Serotonin is synthesized from tryptophan through the action of tryptophan hydroxylase, which converts tryptophan into 5-hydroxytryptophan, followed by decarboxylation to produce serotonin

HUBERMAN: But in addition to that, that you really think about using the minimal effective dose and that you use perhaps even the mildest of these different compounds in order to make sure that you don't desensitize any of the receptor pathways

That uncertainty is a core reason these belong under physician supervision, not self-directed from a website